Varalaxmi S

Publications

• Review Article   
  Nanohybrid-Based Drug Delivery Systems in Cancer Therapy: Advances in Targeted Delivery, Controlled Release, and Translational Challenges
  Author(s): P Sushma* and Varalaxmi S
  
  Nanohybrid-based drug delivery systems have emerged as a promising strategy to overcome the limitations of conventional cancer therapies, including poor solubility, off-target toxicity, and rapid drug clearance. By integrating multiple materials such as polymers, lipids, metals, and inorganic nanostructures, nanohybrids combine the unique advantages of each component, enabling enhanced drug loading, controlled and stimuli-responsive release, and precise tumour targeting. This review provides a comprehensive overview of the current advances in nanohybrid platforms for cancer therapy, highlighting their design principles, preparation methods, mechanisms of action, and therapeutic applications, including chemotherapy, gene delivery, immunotherapy, and theranostics. Key advantages, such as improved pharmacokinetics, reduced systemic toxicity, and multifunctionality, are discussed alongsid.. Read More»
  

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