TN Vijayasree

Publications

• Case Series   
  Photobiomodulation Therapy Mitigates Radiation-Induced Oral Mucositis in Head and Neck Cancer - A Prospective Randomized Study
  Author(s): K C Jyothish*, I Yuvalakshmi, TN Vijayasree and R Giridharan
  
  Background: Oral mucositis is a frequent dose-limiting toxicity during curative head and neck radiotherapy. Photobiomodulation therapy is increasingly used as supportive care; but comparative data against standard topical therapy remain limited. Objectives: To compare 980 nm photobiomodulation therapy with 0.15% benzydamine mouthwash for the prevention and mitigation of radiation-induced oral mucositis in patients with head and neck cancer. Methods: In this prospective randomized open-label phase II study; 40 patients were assigned in a 1:1 ratio to photobiomodulation therapy or benzydamine mouthwash during curative radiotherapy or chemoradiotherapy (60–66 Gy). Oral mucositis was graded serially using the Radiation Therapy Oncology Group scale. Because the supplied workbook did not contain a harmonized numeric pain field; de novo reanalysis focused on mucositis outcomes. Results.. Read More»
  

  Abstract HTML PDF