Meriem Tantaoui

Subatomic Research and Applications Team, Laboratory of the Physics of Condensed Matter (LPMC-ERSA), Faculty of Sciences Ben M’Sick, Hassan II Univers, Morocco

Publications

• Research Article   
  Does the mean heart dose remain a valid parameter for assessing early cardiac toxicity following radiotherapy for left-sided breast cancer?
  Author(s): Nezha Tawfiq*, Salma Guendaoui, Meriem Tantaoui, Karima Bendahhou, Ghita Hatim, Tarik Chekrine, Meryem Belhouari, Mouna Boughafour, Zineb Bouchbika, Nadia Benchakroun, Hassan Jouhadi, Souha Sahraoui, Salah Hayar, Hamza Karmouchi and Rachida Habbal
  
  Context: Adjuvant radiotherapy for left-sided breast cancer improves locoregional control and overall survival. However, irradiation of the cardiac structures increases the risk of radiation-induced cardiotoxicity. The mean heart dose (MHD) is commonly used to estimate this risk, but it does not reflect heterogeneous dose distribution within critical substructures, such as the left ventricle (LV) and left anterior descending artery (LAD). Purpose This study aimed to analyze the dose distribution within cardiac substructures and evaluate the reliability of mean heart dose (MHD) in predicting early radiation-induced myocardial dysfunction. Methods: Fifty patients with left-sided breast cancer who underwent three-dimensional conformal radiotherapy (3D-CRT) at Ibn Rochd University Hospital between 2020 and 2022 were analyzed. The target volumes and cardiac substructures were delineated. T.. Read More»
  

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