Khulood Majid Alsaraf

Publications

• Research Article   
  The human 8-oxoguanine DNA glycosylase and xeroderma pigmentosum group haplotypes variation in x- ray employees
  Author(s): Moayad Aziz Abdulqadir*, Hussain Ghazil, Mariam Alaa Toama, Liwaa Hussein Mahdi, Jamal A. Aljabbar Attawi, Khulood Majid Alsaraf and Zahraa F. Hassan
  
  DNA repair genes polymorphism including The human 8-oxoguanine DNA glycosylase (hOGG ) Ser326Cys and Xeroderma Pigmentosum Group (XPD) Arg399Gln genes in the x-ray employees were studied in present study. PCR-SSCP technique was used to detect haplotype polymorphisms. The results found that the haplotypes distribution of both genes were significant association with cases, XPD have high percentage of di haplotype than control group in significant association (p=0.0019).The hOGG haplotype distribution in study groups shows significant association of di haplotype with cases than control group (P=0.000), both genes haplotypes were distributed according work time in cases per day to more and less than 6 hours, XPD showed non-significant association XPD (p=0.9395), uni and di haplotype more frequent in cases exposure to x-ray less than 6 hours per day. The hOGG appeared in significant associ.. Read More»
  DOI: -

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