Ishita Saha

Department of Physiology, Calcutta Medical College and Hospital, Kolkata, India

Publications

• Research Article   
  Inter-relationship between homeostasis model assessment of insulin resistance & breast cancer biomarkers
  Author(s): Jinseog Kim, Mahashweta Das, Ishita Saha, Prasenjit Sinha, Poonam Singh and Rabindra Nath Das*
  
  The relationship between homeostasis model assessment of insulin resistance (HOMA-IR) and breast cancer (BC) biomarkers such as leptin, monocyte chemoattractant protein-1 (MCP-1), resistin, adiponectin is little known in the medical literature based on probabilistic modeling. The current report focuses on the inter-relationships between HOMA-IR and BC markers. It has been derived from the gamma fitted mean HOMA-IR model that it is higher for healthy women (P<0.0001) than BC patients. It is positively associated with leptin (P=0.0747), while it is negatively associated with the interaction effect of insulin and leptin (insulin*leptin) (P=0.0016). Variance of HOMA-IR is negatively associated with adiponectin (P=0.0471), while it is positively associated with resistin (P=0.0755) and the interaction effect of glucose and adiponectin (glucose*adiponectin) (P=0.0305). From the log-normal.. Read More»
  

  Abstract HTML PDF