R Giridharan

Department of Radiation Oncology, Madras Medical College and Rajiv Gandhi Government General Hospital, Chennai, Tamil Nadu, India

Publications

• Research Article   
  Oesophageal Dose?Volume Parameters and Acute Radiation Oesophagitis in Non-Small Cell Lung Cancer Treated With Definitive Intensity-Modulated Radiotherapy: A Prospective Observational Study
  Author(s): K C Jyothish*, C Ajithaashree, C Saranya, R Giridharan and S Jeva
  
  Background: Acute radiation oesophagitis can impair oral intake, treatment adherence and quality of life during definitive thoracic radiotherapy. Prospective data on oesophageal dose–volume predictors in patients treated with intensity- modulated radiotherapy (IMRT) in Indian practice are limited. Methods: Thirty consecutive patients with stage I–III non-small cell lung cancer (NSCLC) receiving definitive IMRT to 60 Gy in 30 fractions were prospectively evaluated. Oesophageal Dmean, D2cc, V50 and V60 were extracted from planning dose–volume histograms. Acute oesophagitis was graded weekly using Radiation Therapy Oncology Group (RTOG) criteria, and dysphagia was assessed with the Dysphagia Symptom Questionnaire (DSQ). Spearman correlation and exploratory receiver operating characteristic (ROC) analyses were performed. Results: Any-grade oesophagitis occurred in 27/30 .. Read More»
  

  Abstract PDF