M. Mojsak
Laboratory of Molecular Imaging, Nuclear Medicine Department, Medical University of Bialystok, Bialystok, PolandPublications
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Research Article
PET/MRI guided GTV delineation for radiotherapy planning in patients with locally advanced squamous cell carcinoma of the oropharynx and the oral cavity
Author(s): N. Samołyk-Kogaczewska*, E. Sierko*, K. Zuzda, P. Gugnacki, K. Szczecina, D. Dziemianczyk-Pakieła, P. Szumowski, J. Burzynska-Sliwowska and M. Mojsak
Background: Evaluation of possibilities offered by PET/MRI in GTV definition of primary tumors during radiotherapy planning in patients (pts) with locally advanced carcinoma of the oral cavity and the oropharynx. Methods: 15 pts with SCC of the oral cavity and the oropharynx underwent CECT (Aquilion ONE, Toshiba) and PET/MRI (3T Siemens Biograph mMRI) examination. Delineation of GTV was done using two methods: visual interpretation of CT (GTV-CT), PET (GTV-PETvis) and MRI (GTV-MRI) images, as well as the quantitative automatic method (Syngovia, Siemens) based on a selected threshold value (20%, 30%, 40%, 50%) of SUVmax from a PET examination (GTV-PET20%, GTV-PET30%, etc). Obtained volumes were compared and differences were statistically analysed. Results: Statistical analysis demonstrated that GTV-MRI (p=0.0010), GTV-PET20% (p=0.0409), GTV-PET40% (p=0.0309) and GTVPET50% (p=0.0018) d.. Read More»
Editors List
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Ahmed Hussien Alshewered
University of Basrah College of Medicine, Iraq
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Sudhakar Tummala
Department of Electronics and Communication Engineering SRM University – AP, Andhra Pradesh
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Alphonse Laya
Supervisor of Biochemistry Lab and PhD. students of Faculty of Science, Department of Chemistry and Department of Chemis
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Fava Maria Giovanna
- Manuprasad Avaronnan
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