Testicular Embryonal Carcinoma in the patient with undescended testicle


Author(s): Nuraj Petrit* and Oruqi Musa

One 43-year-old male presents in Emergency with left inguinal pain and a mass in the inguinal region. The abdominal surgeon was consulted, who notices a palpation and hard formation in the left inguinal region, which was grown, what raised the suspicion of an incarcerated inguinal hernia. The abdominal surgeon lists the patient for immediate surgical intervention, accessing through the inguinal region. Going through the layers, the formation was reached, which was when it was realized that we are dealing with an undescended testicle tumour. The urologist was called to the surgery room, which then discovers that we are dealing with a tumour of undescended testicle. Left inguinal radical orchiectomy and mass biopsy were performed. Histopathological diagnosis revealed Embryonal carcinoma. Computed tomographic (CT) scan showed multiple metastases: retroperitoneal lymph nodes, and lungs and liver metastasis. Tumour markers elevated; Beta HCG: 1432 mIU/mL, AFP: 409 ng/ml, LDH: 1007 U/L. Chemotherapy was started three weeks after the surgery, with the Bleomycin, Etoposide, and Cisplatin (BEP) regimen, and this cycle was repeated three times, every three weeks, up to three times. After Chemotherapy the tumour markers results were as following: HCG: 4, AFP: 4.8, LDH: 450 U/L. After 3 months CT scan showed, the lungs and liver metastasis seem to have disappeared, and the retroperitoneal lymph nodes were decreased in size. After chemotherapy, retroperitoneal lymph nodes dissection was performed. Microscopic examination revealed no viable cancer cells. After retroperitoneal lymph nodes dissection, the tumour markers results were as following: HCG: 1.0, AFP: 3.6, LDH: 156 U/L. On CT scan, no retroperitoneal, liver, or lungs tumour was detected.


Share this article

Awards Nomination

Editors List

  • Prof. Elhadi Miskeen

    Obstetrics and Gynaecology Faculty of Medicine, University of Bisha, Saudi Arabia

  • Ahmed Hussien Alshewered

    University of Basrah College of Medicine, Iraq

  • Sudhakar Tummala

    Department of Electronics and Communication Engineering SRM University – AP, Andhra Pradesh




  • Alphonse Laya

    Supervisor of Biochemistry Lab and PhD. students of Faculty of Science, Department of Chemistry and Department of Chemis


  • Fava Maria Giovanna


Google Scholar citation report
Citations : 208

Onkologia i Radioterapia received 208 citations as per Google Scholar report

Onkologia i Radioterapia peer review process verified at publons
Indexed In
  • Directory of Open Access Journals
  • Scimago
  • MIAR
  • Euro Pub
  • Google Scholar
  • Medical Project Poland
  • Cancer Index
  • Gdansk University of Technology, Ministry Points 20