Synthesis, Characterization And Cytotoxic Activity Study Of Mn (II), Co (II), And Metal Complexes With New Schiff Base Against The Hepatocellular Carcinoma (SK-GT-4) Cancer Cell

Abstract

Author(s): Zaid N. O. Al-Husseini, Jasim M. S. Alshawi

This paper involved the synthesis of a new compound by condensing O- Phenylenediamine (OPD) and 4-Methyl-o-phenylenediamine with pyrrole-2-carboxaldehyde through a condensation reaction. Following that, transition metal complexes of Mn (II) and Co (II) were prepared by reacting the respective metal chlorides with the ligand in a 1:1 molar ratio. To characterize the ligand and its metal complexes, a comprehensive range of spectroscopic and analytical techniques was employed, confirming their tetrahedral geometry. Additionally, the researchers investigated the potential cytotoxic effects of hepatic cells cancer (SK-GT-4) cancer cells treated with the Schiff bases and its metal compounds.

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Awards Nomination

Editors List

  • Ahmed Hussien Alshewered

    University of Basrah College of Medicine, Iraq

  • Sudhakar Tummala

    Department of Electronics and Communication Engineering SRM University – AP, Andhra Pradesh

     

     

     

  • Alphonse Laya

    Supervisor of Biochemistry Lab and PhD. students of Faculty of Science, Department of Chemistry and Department of Chemis

     

  • Fava Maria Giovanna

     

  • Manuprasad Avaronnan

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