Sister mary joseph's nodule: An important physical finding


Author(s): Parit Cai*, Joviale Christelle Maffo, Mbachan Masoeli Takere and Elroy Patrick Weledji

Background: Sister Mary Joseph’s nodule is a rare but important physical pending as it is a sign of an advanced stage of malignancy.

Case presentation: This is a case of an apparently clinically well but immune- deficient 62-year-old African woman whose main complaint was an enlarging violaceous discharging umbilical nodule. A focused history and physical examination complemented by an abdominal Computerized Tomography (CT) scan was sug-gestive of an umbilical cutaneous manifestation (Sister Mary Joseph’s nodule) of an underlying disseminated ovarian malignancy. This was confirmed histologically by an excision biopsy of the umbilical nodule.

Conclusion: Sister Mary Joseph’s nodule is an important differential diagnosis for an umbilical nodular lesion as it is a sign of advanced malignancy with a generally poor prognosis. [profil a�?k i�erik kabul etmiyor][eklenecek yer buylamad?m][eklenecek yer yok]

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Awards Nomination

Editors List

  • Prof. Elhadi Miskeen

    Obstetrics and Gynaecology Faculty of Medicine, University of Bisha, Saudi Arabia

  • Ahmed Hussien Alshewered

    University of Basrah College of Medicine, Iraq

  • Sudhakar Tummala

    Department of Electronics and Communication Engineering SRM University – AP, Andhra Pradesh




  • Alphonse Laya

    Supervisor of Biochemistry Lab and PhD. students of Faculty of Science, Department of Chemistry and Department of Chemis


  • Fava Maria Giovanna


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