Sister mary joseph's nodule: An important physical finding
Background: Sister Mary Joseph’s nodule is a rare but important physical pending as it is a sign of an advanced stage of malignancy.
Case presentation: This is a case of an apparently clinically well but immune- deficient 62-year-old African woman whose main complaint was an enlarging violaceous discharging umbilical nodule. A focused history and physical examination complemented by an abdominal Computerized Tomography (CT) scan was sug-gestive of an umbilical cutaneous manifestation (Sister Mary Joseph’s nodule) of an underlying disseminated ovarian malignancy. This was confirmed histologically by an excision biopsy of the umbilical nodule.
Conclusion: Sister Mary Joseph’s nodule is an important differential diagnosis for an umbilical nodular lesion as it is a sign of advanced malignancy with a generally poor prognosis.
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Prof. Elhadi Miskeen
Obstetrics and Gynaecology Faculty of Medicine, University of Bisha, Saudi Arabia
Ahmed Hussien Alshewered
University of Basrah College of Medicine, Iraq
Department of Electronics and Communication Engineering SRM University – AP, Andhra Pradesh
Supervisor of Biochemistry Lab and PhD. students of Faculty of Science, Department of Chemistry and Department of Chemis
Fava Maria Giovanna
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