Role of Serum Prostatic Acid Phosphatase on Prostate Cancer Patients


Author(s): Jinseog Kim, Mahashweta Das, Ishita Saha, Gaurab Bhattacharyya, Sabyasachi Mukherjee, Ranjan Kumar Sahoo, Rajyalakshmi Kottapalli, Rajkumari Sanatombi Devi, Sunit Kumar Medda and Rabindra Nath Das*

It is well known that serum prostatic acid phosphatase (SPAP) may have a great role on Prostate Cancer Patients (PCPs), but its effects are not clearly identified in the prostate cancer literature. The current article aims to identify the effects of SPAP on PCPs. It is derived herein that mean SPAP level is higher for PCPs (P<0.0001) and PCPs confined to bed (P=0.0794) than normal. Mean SPAP level is higher for PCPs with Bone Metastases (BM) (P<0.0001), and it is lower for cardiovascular disease history patients (CDHPs) (P=0.0188) than normal. Mean SPAP level is positively connected with estrogen level (P=0.1148) in the log-normal fitted model, while it is highly significant (P<0.0001) in the gamma fitted model. In addition, mean SPAP level is positively related with Serum Hemoglobin (SHG) (P=0.0167), size of primary tumor (P=0.0092) and study time (P=0.0463). Variance of SPAP level is higher scattered for PCPs (P<0.0001), and PCPs with BM (P=0.0005), or CDHPs (P=0.0113) than normal. Again, variance of SPAP level is positively related with diastolic blood pressure (DBP) (P=0.0433), estrogen level (P=0.0225), size of primary tumor (SZ) (P=0.0915) and index of tumor stage and histolic grade (SG) (P=0.0155), while it is negatively connected with electrocardiogram status (P=0.0229) and SHG (P=0.0340). The report concludes that SPAP is highly associated with PCPs and along with their many factors such as SHG, estrogen level, BM, size of primary tumor, DBP etc.

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Awards Nomination

Editors List

  • Prof. Elhadi Miskeen

    Obstetrics and Gynaecology Faculty of Medicine, University of Bisha, Saudi Arabia

  • Ahmed Hussien Alshewered

    University of Basrah College of Medicine, Iraq

  • Sudhakar Tummala

    Department of Electronics and Communication Engineering SRM University – AP, Andhra Pradesh




  • Alphonse Laya

    Supervisor of Biochemistry Lab and PhD. students of Faculty of Science, Department of Chemistry and Department of Chemis


  • Fava Maria Giovanna


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