Optimizing Helicobacter pylori diagnosis in oncology for enhanced radiotherapy outcomes

Abstract

Author(s): Shier Ali Khorsheed*

Helicobacter pylori consider a globally common infection, and closely related to the occurrence of stomach cancers. Since accurate diagnosis is a key factor in eradicating this infection, so this study aimed to conduct a comparison between the serology with the stool analyses for the identification of this infection. Sixty patients with dyspepsia and sixty others participated as controls in this comparative study, no statistical variation was noted between the groups in terms of gender and age. Samples required for serology (IgM) and Stool Antigen Test (SAT) were collected. The results confirmed that the prevalence of infection among all participants 120 was 61.7% and 70.0% depending on serology and SAT methods, respectively. Patients were more positive towards SAT 41.7%, compared to the controls 28.3% with a considerable difference p=0.003. Likewise for serology test, where 37.5% of the patients compared to 25.8% of the controls were positive (p=0.001). It was concluded that both serology and SAT tests of Helicobacter pylori are useful in the diagnosis of infection, and are somewhat comparable in their ability to detect infection especially in suspected endemic areas.

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