Influencing factors of FEV1 and FVC for primary lung cancer patients

Abstract

Author(s): Jinseog Kim, Rabindra Nath Das*, Youngjo Lee and Sabyasachi Mukherjee

The determinants of FEV1 and FVC of 470 primary lung cancer patients with 17 characters who underwent major lung resections have been derived in the report. The mean FEV1 is positively associated with FVC (p<0.0001), and it is negatively associated with performance status at level 2 (p=0.0092), level 3 (p=0.0196), while its variance is positively associated with haemoptysis (p<0.0001), dyspnoea (p<0.0001), and it is negatively associated with FVC (p<0.0001), age (p<0.0001), performance status at level 2 (p<0.0001), level 3 (p<0.0001). On the other hand, mean FVC is negatively associated with age (P<0.0001), performance status at level 2 (p=0.0431), haemoptysis (p=0.0351), diabetes mellitus (p=0.0276), asthma (p<0.0001), while it is positively associated with diagnosis (p=0.0032) and cough (p=0.0676). Younger lung cancer patients with no advanced diseases such as asthma, diabetes mellitus, haemoptysis have higher FVC or FEV1. Care should be taken for advanced disease lung cancer patients during lung resection.

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Editors List

  • Osamu Tanaka

    Osamu Tanaka
    Assistant Professor,
    Department of Radiation Oncology
    Asahi University Hospital
    Gifu city, Gifu, Japan

  • Maher Abdel Fattah Al-Shayeb

    Department of Surgical Sciences, Ajman University, UAE

  • Andrzej Zdziennicki

    Institute of Gynecology and Obstetrics, Medical University of Lodz, I Clinic of Gynecology and Gynecological Oncology (Lodz, Poland)

  • Krzysztof Urbanski

    Head of the Oncology Gynecology Clinic, Oncology Center - Instytut im. Maria Sklodowska Curie, Department in Krakow (Krakow, Poland)

  • Andrzej Szawlowski

    Klinika Nowotworow Gornego Odcinka Uklad Digestii, Oncology Center - Institute (Warsaw, Poland)