Expression of sortilin in pancreatic carcinoma and influence of pancreatic cancer cells by sortilin sirna knockdown
Author(s): Astrit Gashi
Background: Currently, there are few effective therapeutic options for pancreatic cancer patients.Sortilin is a member of vps10p receptor family?reported in many types of cancers.However, the underlying mechanism and prognostic value of sortilin in pancreatic cancer are still unclear. Objective:Understand the expression of sortilin in pancreatic cancer, and analyze its mechanism that affects the occurrence and development of pancreatic cancer. Abbreviations: PC:Pancreatic cancer;ROC:the receiver operating characteristic;SEIN:Sortilin expression in nucleus;NTs:Neurotrophic factor family;min:minute;sec:second;BLR:Binary Logistic Regression ;siRNA:small interference RNA;IHC:Immunohistochemistry;RTPCR:Reverse Transcription Polymerase Chain Reaction.
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Submitted PhD thesis in Biotechnology at GITAM University, Vizag.
The Past Head, General Administration of Pharmaceutical Care at Ministry of Health,
Saudi Arabia Critical Care/TPN
Clinical Pharmacist Ministry of Health,
Riyadh, Saudi Arabia.
Department of Radiation Oncology
Asahi University Hospital
Gifu city, Gifu, Japan
Maher Abdel Fattah Al-Shayeb
Department of Surgical Sciences, Ajman University, UAE
Institute of Gynecology and Obstetrics, Medical University of Lodz, I Clinic of Gynecology and Gynecological Oncology (Lodz, Poland)
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