Cutaneous relapse after primary breast lymphoma remission

Abstract

Author(s): Jiyoung Yun*

Primary breast lymphoma is a rare extra-nodal lymphoma that accounts for only 0.4%-0.5% of all breast malignancies. Cases with only skin recurrence without primary site involvement after remission are rarer. In this case, a 49-year-old woman was diagnosed with diffuse large B-cell lymphoma of the left breast, which was in complete remission after chemotherapy. One year later, she requested excisional biopsy of a subcutaneous cyctic lesion in the posterior neck area on ultrasound. As a result of the surgical biopsy, the pathologic findings were diffuse large B-cell lymphoma. Treatment was completed after seventeen fractions of radion therapy without further wide excision. This is an important case because relapse of primary breast lymphoma without primary site involvement is rare and the isolated relapse at another site may have been misdiagnosed as a transient inflammatory cyst in the skin layer.

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