Comparison study for IMRT, VMAT and 3D conformal in the treatment of gastric cancer patients


Author(s): Islam Makhtar*, Mahmoud EL Ghassaly, Ehab Abdouh and Khaled El-Shahat

The goal of the current study was to compare radiotherapy treatment plans for gastric cancer using double-arc volumetric (VMAT), Intensity-Modulated Radiotherapy (IMRT) versus 3DCRT delivery techniques. Materials and Methods: A total of 20 gastric cancer patients were involved in current study and each patient was scheduled IMRT VMAT and 3DCRT techniques. Dose-volume histogram statistics, Conformal Index (CI), hand Monitor Units (MUs) were analysed to compare treatment plans, treatment planning system eclipse Algorithm AAA with Energy true beam linear accelerator Varian model. Results and Discussion: The VMAT plans exceeded the other two techniques for coverage planning tumour volume dose and reduction dose for organs at risk in the kidneys, but not in the liver. VMAT exhibited a better mean CI (0.89±0.03), than the other techniques. In addition, for the kidneys the dose sparing (V13, V18 and mean kidney dose) was improved by VMAT plans. However, IMRT showed a marginal advantage in V30 and mean dose in normal liver when compared with VMAT. Conclusion: This study suggests that VMAT provides improved tumour coverage when compared with IMRT, and 3DCRT however, VMAT haven’t any advantage in liver protection when compared with IMRT. Furthermore, studies are required to establish differences in treatment outcomes among the four technologies

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Editors List


    Submitted PhD thesis in Biotechnology at GITAM University, Vizag.

  • Yousef Alomi

    Yousef Alomi
    The Past Head, General Administration of Pharmaceutical Care at Ministry of Health,
    Saudi Arabia Critical Care/TPN
    Clinical Pharmacist Ministry of Health,
    Riyadh, Saudi Arabia.

  • Osamu Tanaka

    Osamu Tanaka
    Assistant Professor,
    Department of Radiation Oncology
    Asahi University Hospital
    Gifu city, Gifu, Japan

  • Maher Abdel Fattah Al-Shayeb

    Department of Surgical Sciences, Ajman University, UAE

  • Andrzej Zdziennicki

    Institute of Gynecology and Obstetrics, Medical University of Lodz, I Clinic of Gynecology and Gynecological Oncology (Lodz, Poland)

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