Comparison of epidemiological criteria for colorectal cancer over 10 years: incidence, therapeutic management and overall survival

Abstract

Author(s): Youssef Elhaitmy*, Zineb Benbrahim, Soukaina El Anssari, fatimazahra Bartal, Lamiae Amaadour, Karima Oualla, Samia Arifi and Nawfel Mellas

Colorectal Cancer (CRC) is ranked among the most common cancers in the world, third after breast and prostate cancer and second digestive cancer in Morocco after gastric cancer. However, its incidence in our country remains lower than that of Western countries (2.5 to 3.3/100,000 ha). Knowledge of the epidemiological characteristics of CRC will certainly condition our therapeutic attitudes. The aim of this article is to compare the epidemiological, anatomopathological and therapeutic characteristics over ten years and to show that progress in recent years in terms of treatment has contributed to the increase in survival rates. We included 571 patients in a retrospective study with CRC treated at the medical oncology department of Fez over a period from June 2014 to June 2023. The Kaplan Meier method was used to estimate the median survival. There is a slight male predominance. The average age in our study at the time of diagnosis was 59 years. The time between the onset of symptoms and the consultation was mostly more than 6 months between the first two years of the study and was less than 3 months in the last two years. Clinical symptoms were dominated by transit disorders, rectal bleeding and weight loss. Median Overall Survival (OS) was 22.3 months ± 0.6 CI (21-23.6) between 2014-2016 vs. 28.3 months ± 0.6 CI (24-29.6) between 2021-2023. We reported an improvement in Progression Free Survival (PFS) in the last two years (192 months ± 0.6 CI (19–21) vs. 16,4 months ± 0.4 CI (16-20). Our study showed an increase in overall survival and progression free survival over the past ten years.

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