Znaczenie systemu antyoksydacyjnego w różnych schorzeniach ginekologicznych – przegląd piśmiennictwa


Author(s): Anita Olejek, Jacek ZamlyÅ?ski, Agnieszka Jurek, Piotr Bodzek, Bogdan Szymala, Leszek Nowak

Oxidative stress is due to a disturbance in the balance between the production of reactive oxygen species and the efficiency of the antioxidant defense. Oxidative stress has been implicated in playing a crucial role in the pathogenesis of many diseases, including gynecological disorders, aging and in the initiation and progression of cancer. Reactive oxygen species may modify and inactivate proteins, lipids, DNA, RNA and induce cellular dysfunctions. To prevent free radical- induced cellular damage, the organism has developed the antioxidative system. Antioxidants can generally be divided into two categories: enzymatic and non-enzymatic. In the present study, we describe the changes of antioxidant enzyme activities in many gynecological disorders.

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Editors List


    Submitted PhD thesis in Biotechnology at GITAM University, Vizag.

  • Yousef Alomi

    Yousef Alomi
    The Past Head, General Administration of Pharmaceutical Care at Ministry of Health,
    Saudi Arabia Critical Care/TPN
    Clinical Pharmacist Ministry of Health,
    Riyadh, Saudi Arabia.

  • Osamu Tanaka

    Osamu Tanaka
    Assistant Professor,
    Department of Radiation Oncology
    Asahi University Hospital
    Gifu city, Gifu, Japan

  • Maher Abdel Fattah Al-Shayeb

    Department of Surgical Sciences, Ajman University, UAE

  • Andrzej Zdziennicki

    Institute of Gynecology and Obstetrics, Medical University of Lodz, I Clinic of Gynecology and Gynecological Oncology (Lodz, Poland)

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