Zastosowanie rezonansu magnetycznego w ocenie stopnia zaawansowania pacjentow z nowo zdiagnozowanym rakiem gruczolu krokowego

Abstract

Author(s): Maciej Harat, Andrzej Lebioda, Tomasz Wisniewski, Roman Makarewicz

Purpose: According to 2012 NCCN Guidelines pelvic magnetic resonance imaging (MRI) scanning is recommended in stage T3 or T4 of prostate cancer, or T1 or T2 disease and a nomogram indicates there is greater than 20% chance of lymph node involvement. This study was formed to determine the relative benefits of using MRI in final staging of patients with newly diagnosed prostate cancer.

Methods: 174 patients were reviewed between year 2007 - 2011. All patients included in the study underwent biopsy, TRUS and MRI during process of diagnosis of prostate cancer in Oncology Centre in Bydgoszcz. Patients were analyzed due to international risk group, age, pathological type of tumor, tumor localization, Gleason score, PSA level, previous hormonotherapy. Information received were compared with MRI results obtained at the time of diagnosis.

Results: Analysis showed that MRI changed staging of 90 patients with prostate cancer (52%). There were no significant changes in 84 cases using MRI comparing to previous staging based on clinical examination, TRUS and biopsy. Variance analysis showed a significant correlation between restaging , T2 stage and PSA max value (p<0,028). In each NCCN risk group (T stage, PSA level, Gleason score) there existed MRI findings that changed final stage. The results were not connected with previous hormonotherapy or tumor localization in the gland.

Conclusions: The study showed that MRI is a useful method in final staging of prostate cancer patient before radical radiotherapy. We failed to identify a significant factor or group of factors which strictly indicate that diagnostic MRI can be omitted.

<

Share this article

Awards Nomination

Editors List

  • Prof. Elhadi Miskeen

    Obstetrics and Gynaecology Faculty of Medicine, University of Bisha, Saudi Arabia

  • Ahmed Hussien Alshewered

    University of Basrah College of Medicine, Iraq

  • Sudhakar Tummala

    Department of Electronics and Communication Engineering SRM University – AP, Andhra Pradesh

     

     

     

  • Alphonse Laya

    Supervisor of Biochemistry Lab and PhD. students of Faculty of Science, Department of Chemistry and Department of Chemis

     

  • Fava Maria Giovanna

     

Google Scholar citation report
Citations : 2495

Onkologia i Radioterapia received 2495 citations as per Google Scholar report

Onkologia i Radioterapia peer review process verified at publons
Indexed In
  • Scimago
  • SCOPUS
  • MIAR
  • Euro Pub
  • Google Scholar
  • Medical Project Poland
  • PUBMED
  • Cancer Index
  • Gdansk University of Technology, Ministry Points 20