Wyniki pooperacyjnej radioterapii chorych na obloniaki ??ródczaszkowe. Trzydzie??ci lat do??wiadcze?? Centrum Onkologii w Krakowie, 1975-2005
Abstract
Author(s): Bogdan GliĆ ?ski, Elà ¼bieta Pluta, Pawel Dymek, Anna Mucha-Malecka, Beata FrĆ?czek-Blachut, Jacek UrbaĆ ?ski, agdalena Jarosz, Dariusz Martynów
Introduction: Hemangiopericytoma is an extremely rare mesenchymal tumour that most often arises among the meningeal surface of the brain. It is an aggressive neoplasm with high rate of local recurrence and direct metastatic spread. Surgery followed by radiation therapy is the treatment of choice.
Objectives: The aim of this study was to assess the efficacy of postoperative radiotherapy of intracranial hemangiopericytoma. Material and methods. Over the period of thirty years, 24 adult patients with intracranial hemangiopericytomas received postoperative irradiation at the Center of Oncology in Cracow. The total tumor dose was 60 Gy delivered in 30 fractions in 6 weeks.
Results: The five- year survival without evidence of disease (NED) in the whole group was 25% (6 of 24 cases treated). Patients with severe neurologic impairments (status 3, according to the EORTC/MRC neurologic deficit score) carried the worst prognosis. Median survival time in this group was 26 months, compared to 40 months for other patients.
Conclusions: The results of the current study suggest, that postoperative radiotherapy in hemangiopericytomas should be mainly given in patients with neurologic deficits defined as 1 and 2 in the EORTC/MRC neurological scale function.
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Editors List
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S.SREEDHAR
Submitted PhD thesis in Biotechnology at GITAM University, Vizag.
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Yousef Alomi
Yousef Alomi
The Past Head, General Administration of Pharmaceutical Care at Ministry of Health,
Saudi Arabia Critical Care/TPN
Clinical Pharmacist Ministry of Health,
Riyadh, Saudi Arabia. -
Osamu Tanaka
Osamu Tanaka
Assistant Professor,
Department of Radiation Oncology
Asahi University Hospital
Gifu city, Gifu, Japan -
Maher Abdel Fattah Al-Shayeb
Department of Surgical Sciences, Ajman University, UAE
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Andrzej Zdziennicki
Institute of Gynecology and Obstetrics, Medical University of Lodz, I Clinic of Gynecology and Gynecological Oncology (Lodz, Poland)
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