Wyniki pooperacyjnej radioterapii chorych na obloniaki ??r�dczaszkowe. Trzydzie??ci lat do??wiadcze?? Centrum Onkologii w Krakowie, 1975-2005
Author(s): Bogdan GliÅ?ski, ElÅ¼bieta Pluta, Pawel Dymek, Anna Mucha-Malecka, Beata FrÄ?czek-Blachut, Jacek UrbaÅ?ski, agdalena Jarosz, Dariusz MartynÃ³w
Introduction: Hemangiopericytoma is an extremely rare mesenchymal tumour that most often arises among the meningeal surface of the brain. It is an aggressive neoplasm with high rate of local recurrence and direct metastatic spread. Surgery followed by radiation therapy is the treatment of choice.
Objectives: The aim of this study was to assess the efficacy of postoperative radiotherapy of intracranial hemangiopericytoma. Material and methods. Over the period of thirty years, 24 adult patients with intracranial hemangiopericytomas received postoperative irradiation at the Center of Oncology in Cracow. The total tumor dose was 60 Gy delivered in 30 fractions in 6 weeks.
Results: The five- year survival without evidence of disease (NED) in the whole group was 25% (6 of 24 cases treated). Patients with severe neurologic impairments (status 3, according to the EORTC/MRC neurologic deficit score) carried the worst prognosis. Median survival time in this group was 26 months, compared to 40 months for other patients.
Conclusions: The results of the current study suggest, that postoperative radiotherapy in hemangiopericytomas should be mainly given in patients with neurologic deficits defined as 1 and 2 in the EORTC/MRC neurological scale function.<
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Prof. Elhadi Miskeen
Obstetrics and Gynaecology Faculty of Medicine, University of Bisha, Saudi Arabia
Ahmed Hussien Alshewered
University of Basrah College of Medicine, Iraq
Department of Electronics and Communication Engineering SRM University – AP, Andhra Pradesh
Supervisor of Biochemistry Lab and PhD. students of Faculty of Science, Department of Chemistry and Department of Chemis
Fava Maria Giovanna
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