The cause of antimicrobial resistant in enterobacterales pathogens displacement from patients of gastrointestinal cancer

Abstract

Author(s): Aqeel Abbas Kareem* and Heyam Qaid Muhammed

Background: Bacterial infections associated with multidrug resistance have been implicated in high mortality and morbidity reported among cancer patients. Aim: The purpose of this research was to determine the function that betalactam played in the colonization of specific Enterobacterales strains of bacterial infection associated with MDR. Material and Methods: Patients diagnosed with colon cancer each provided a sample of their feces, totaling forty, while the remaining fifty samples served as a control. These specimens were cultivated on MacConkey agar and kept in an incubator at 37 degrees Celsius for a period of 24 hours. Following this, antimicrobial susceptibility testing utilizing the disc diffusion technique was carried out. Results: The analysis revealed that 40 out of the 50 samples had a positive outcome. It appear that Escherichia coli and Klebsiella pneumonia were the most common bacteria that were isolated, and the results revealed that the most of bacterial isolates exhibited resistance to Beta –lactam antibiotics. Conclusion: All of the bacteria that were isolated and analyzed were MDR (Multiple drug resistance). Consequently, these organisms constitute a difficult treatment challenge for those who have Gastrointestinal cancer.

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