Skuteczno???? paliatywnej teleradioterapii w stosunku do objaw�w zwi??zanych z miejscowym rozrostem niedrobnokom�rkowego raka pluca. Analiza 1350 chorych
Author(s): Tomasz Walasek, Marian Reinfuss, Jerzy Jakubowicz, Piotr Skotnicki, Pawel Blecharz, Marcin Hetnal, ElÅ¼bieta Pluta, Andrzej Kukielka, Piotr Brandys
Purpose: To assess palliative effect of chest teleradiotherapy in reducing symptoms of locoregional tumor growth in patients with advanced non-small cell lung cancer.
Materials and methods: Analysis was conducted in the group of 1350 patients with disturbing, moderate to severe symptoms: cough in 45,2% of patients, hemoptysis – 20%, chest pain - 18,5%, dyspnoea – 14,4%, hoarseness - 8,1% and swallowing difficulties – 6,0%. Patients were included in the symptomatic response assessment. Good palliative effect of the treatment were disappearance (CR) or improvement (PR) of a most disturbing symptom of at least 1 point in 4 point scale (0 – without symptoms, 1 – mild, 2 – moderate, 3 – severe symptoms).
Results: The best palliative effect was obtained in patients suffering from hemoptysis (CR=70%, CR+PR=84%), chest pain (CR=60,8%, CR+PR=72%) and in patients with cough (CR=34,9%, CR+PR=64,9%). Relatively good palliative effect was obtained in patients with dyspnoea (CR + PR=42,1%) and hoarseness (CR+PR=35,5%), weak palliative effect in patients with swallowing difficulties (CR+PR=14,8%).
Conclusions: Palliative teleradiotherapy was effective in reducing hemoptysis, cough and chest pain, less effective in reducing dyspnoea and hoarseness and not enought effective in patinets with swallowing disturbances.<
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Prof. Elhadi Miskeen
Obstetrics and Gynaecology Faculty of Medicine, University of Bisha, Saudi Arabia
Ahmed Hussien Alshewered
University of Basrah College of Medicine, Iraq
Department of Electronics and Communication Engineering SRM University – AP, Andhra Pradesh
Supervisor of Biochemistry Lab and PhD. students of Faculty of Science, Department of Chemistry and Department of Chemis
Fava Maria Giovanna
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