Risk of hepatocellular carcinoma due to aflatoxin infested areca nut consumption-a review


Author(s): Suwarna Dangore Khasbage, Rahul R. Bhowate, Swapnil C. Mohod, Mrunal Meshram

Areca nut (AN) consumption is a practice of great antiquity in India and reported to be consumed by 20 to 30% of the Indian population in last 2-3 decades. Various mechanisms have been reported with reference to its adverse effects on the liver, one of which could be ingestion of aflatoxin infected AN, as aflatoxin B1 is a known hepatotoxin. Reports are available stating that the most of the ANs available in the market are substandard and contaminated with cancer- causing fungus and chewing of such poor quality, infested ANs would definitely pose severe health problems on human beings in a long time. But, to our knowledge scanty literature is available reporting the role of aflatoxin infested AN on risk of liver cancer. The evolution of such risk factors provides insight into understanding of the future burden of the disease.

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Awards Nomination

Editors List

  • Prof. Elhadi Miskeen

    Obstetrics and Gynaecology Faculty of Medicine, University of Bisha, Saudi Arabia

  • Ahmed Hussien Alshewered

    University of Basrah College of Medicine, Iraq

  • Sudhakar Tummala

    Department of Electronics and Communication Engineering SRM University – AP, Andhra Pradesh




  • Alphonse Laya

    Supervisor of Biochemistry Lab and PhD. students of Faculty of Science, Department of Chemistry and Department of Chemis


  • Fava Maria Giovanna


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