Odlegle wyniki radioterapii chorych na naczyniakowlókniaka mlodzieńczego

Abstract

Author(s): Elżbieta Pluta, Maria Marczak-Ziętkiewicz, Bogdan Gliński

Purpose: To update our experience and to determine the efficacy of radiation therapy for juvenile nasopharyngeal angiofibroma.

Materials and methods: Twelve patients with juvenile nasopharyngeal angiofibroma received radiation therapy between 1974 and 2004. Three patients had a definitive radiotherapy, nine were irradiated postoperatively. A total dose ranged from 30 to 50 Gy. All patients had a six year minimum follow-up (median: 19 years).

Results: Local control (complete and partial regression) after radiotherapy was obtained in 9 patients (75%). The median time to regression was 13 months (range, 4 to 29 months). Late complications included cataracts in 2 patients, and abnormal development of the craniofacial skeleton in 1 patient.

Conclusions: Radiotherapy is an effective treatment for juvenile angiofibroma. Tumor regression occurs slowly over several months.

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