Ocena wyników i metod pooperacyjnego napromieniania złośliwych glejaków mózgu



Introduction: The aim of the study was evaluation of results and methods of postoperative irradiation patients suffering on malignant brain gliomas. Retrospective analysis of 206 patients treated in Centrum Onkologii Ziemi Lubelskiej in 1992-2002 has been carried out.

Material and methods: All patients passed operative treatment. In 54% radical operation was performed, 46% of patents underwent palliative operation. The most frequently occurring microscopic form was glioblastoma multiforme - 72%. The patients were treated in conditions of teleradiotherapy with two methods: conventional dose fractionation and unconventional, so called method of “series”.

Results: 5-years-long total survivals were evaluated in examined group of patients. Analysis of 5- year-long total survival rates was performed by Kaplan-Meier’s method. Mean value of survival time amounted to 11.5 months. Survival time of examined patients depends essentially on the method of irradiation. Median of total survival time of conventional dose fractionation method is 11 months while median of total survival time of patients unconventionally irradiated is 6.5 months. Results of postoperative irradiation of malignant brain gliomas are bad.

Conclusions: Method of radiotherapy is a fundamental prognostic factor.

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Editors List

  • Osamu Tanaka

    Osamu Tanaka
    Assistant Professor,
    Department of Radiation Oncology
    Asahi University Hospital
    Gifu city, Gifu, Japan

  • Maher Abdel Fattah Al-Shayeb

    Department of Surgical Sciences, Ajman University, UAE

  • Andrzej Zdziennicki

    Institute of Gynecology and Obstetrics, Medical University of Lodz, I Clinic of Gynecology and Gynecological Oncology (Lodz, Poland)

  • Krzysztof Urbanski

    Head of the Oncology Gynecology Clinic, Oncology Center - Instytut im. Maria Sklodowska Curie, Department in Krakow (Krakow, Poland)

  • Andrzej Szawlowski

    Klinika Nowotworow Gornego Odcinka Uklad Digestii, Oncology Center - Institute (Warsaw, Poland)