Żóltakogwiaździak wielopostaciowy: obraz kliniczny, leczenie, rokowanie. Przegląd literatury


Author(s): Anna Mucha-Malecka, Bogdan Gliński, Krzysztof Malecki1, Krzysztof Roszkowski, Marta Urbańska-Gąsiorowska

Pleomorphic xanthoastrocytoma (PXA) is a superficial, circumscribed rare glial tumor with the typical location in the cerebral hemispheres, particularly in the temporal and parietal lobes. Microscopic features include marked cellular pleomorphism, nuclear atypia, increased mitotic index and presence of necrosis. It affects children and young adults, and has a relatively favorable prognosis with ten-years relapse- free survival, and overall survival of 61% and 70% respectively. Surgery remains the mainstay of treatment, the roles of adjuvant irradiation and chemotherapy remains undefined. Radiotherapy with total doses of 30-60 Gy, delivered in the conventional fractionation regimen is recommended after subtotal resection, and in patients who have anaplastic variant of PXA. Extent of resection, the value of mitotic index and presence of necrosis are the recognized factors influencing clinical outcome.


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Awards Nomination

Editors List

  • Prof. Elhadi Miskeen

    Obstetrics and Gynaecology Faculty of Medicine, University of Bisha, Saudi Arabia

  • Ahmed Hussien Alshewered

    University of Basrah College of Medicine, Iraq

  • Sudhakar Tummala

    Department of Electronics and Communication Engineering SRM University – AP, Andhra Pradesh




  • Alphonse Laya

    Supervisor of Biochemistry Lab and PhD. students of Faculty of Science, Department of Chemistry and Department of Chemis


  • Fava Maria Giovanna


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