Liver transplantation for primary intrahepatic adenosquamous carcinoma using a marginal graft
Background: Primary Intrahepatic Adenosquamous Carcinoma (iASC) is a very rare subtype of Cholangiocarcinoma (CCA), with a worse prognosis than adenocarcinoma. Hepatectomy is still the first choice for iASC, and Liver Transplantation (LT) for iASC has not been previously reported.
Case presentation: The young male patient with an unresectable primary iASC underwent a LT using a marginal fatty liver graft. The overall survival of this patient was 16 months, with a recurrence-free survival of 8 months. The patient had a good quality of life with normal liver function until 3 months before death.
Conclusion: This is the first case report of LT as treatment of unresectable iASC using a marginal graft, by which our patient gained a longer survival. Although the recipient may benefit from LT, LT for iASC should proceed with caution owing to its more aggressive features.
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Prof. Elhadi Miskeen
Obstetrics and Gynaecology Faculty of Medicine, University of Bisha, Saudi Arabia
Ahmed Hussien Alshewered
University of Basrah College of Medicine, Iraq
Department of Electronics and Communication Engineering SRM University – AP, Andhra Pradesh
Supervisor of Biochemistry Lab and PhD. students of Faculty of Science, Department of Chemistry and Department of Chemis
Fava Maria Giovanna
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