Leczenie systemowe przerzutow do mozgu u chorych na czerniaka
Abstract
Author(s): Ida Cedrych, Marian Reinfuss, Marek Jasiowka, Jerzy Jakubowicz, Pawel Blecharz, Tomasz Walasek
Based on literature data we discussed systemic treatment of brain metastases in patients with melanoma. It has been shown that among cytotoxic drugs only fotemustine and temozolomide showed real but relatively low effect. Small profit yielded application trials of interleukin 2 and interferon alfa-2b, as well as adaptive therapy. The possibility of improving the outcome of melanoma patients with brain metastases was created by entering into clinical practice CTLA4 monoclonal antibodies and inhibitors of serine threonine kinases.
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Editors List
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Prof. Elhadi Miskeen
Obstetrics and Gynaecology Faculty of Medicine, University of Bisha, Saudi Arabia
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Ahmed Hussien Alshewered
University of Basrah College of Medicine, Iraq
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Sudhakar Tummala
Department of Electronics and Communication Engineering SRM University – AP, Andhra Pradesh
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Alphonse Laya
Supervisor of Biochemistry Lab and PhD. students of Faculty of Science, Department of Chemistry and Department of Chemis
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Fava Maria Giovanna
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