Leczenie systemowe przerzutow do mozgu u chorych na czerniaka


Author(s): Ida Cedrych, Marian Reinfuss, Marek Jasiowka, Jerzy Jakubowicz, Pawel Blecharz, Tomasz Walasek

Based on literature data we discussed systemic treatment of brain metastases in patients with melanoma. It has been shown that among cytotoxic drugs only fotemustine and temozolomide showed real but relatively low effect. Small profit yielded application trials of interleukin 2 and interferon alfa-2b, as well as adaptive therapy. The possibility of improving the outcome of melanoma patients with brain metastases was created by entering into clinical practice CTLA4 monoclonal antibodies and inhibitors of serine threonine kinases.

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Editors List


    Submitted PhD thesis in Biotechnology at GITAM University, Vizag.

  • Yousef Alomi

    Yousef Alomi
    The Past Head, General Administration of Pharmaceutical Care at Ministry of Health,
    Saudi Arabia Critical Care/TPN
    Clinical Pharmacist Ministry of Health,
    Riyadh, Saudi Arabia.

  • Osamu Tanaka

    Osamu Tanaka
    Assistant Professor,
    Department of Radiation Oncology
    Asahi University Hospital
    Gifu city, Gifu, Japan

  • Maher Abdel Fattah Al-Shayeb

    Department of Surgical Sciences, Ajman University, UAE

  • Andrzej Zdziennicki

    Institute of Gynecology and Obstetrics, Medical University of Lodz, I Clinic of Gynecology and Gynecological Oncology (Lodz, Poland)

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