Inherited thrombophilia in a patient with a colorectal carcinoma-a case report.


Author(s): Hrnčár Matej, Breznický Jozef, Chudej Juraj, Sokol Juraj, Staško Ján

Background: The incidence of thrombotic complications in patients with malignancy is higher than in the general population. There is little data about the association of congenital thrombophilia with malignant disease. Methodology: We report a 48 years old patient with inherited thrombophilia (homozygous factor V Leiden and homozygous MTHFR C677T) with the manifestation of thromboembolic disease who developed colorectal carcinoma seventeen years after diagnosis of thrombotic events. Discussion: We discuss the need for cancer screening in patients with inherited thrombophilia as the need for thromboprophylaxis in patients with inherited thrombophilia and cancer. Conclusion: We now have to focus on clinical experience and think about the possibility of cancer in patients with congenital thrombophilia. In case of any suspicion, adequate investigation is needed to detect the early stage of the disease

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Awards Nomination

Editors List

  • Prof. Elhadi Miskeen

    Obstetrics and Gynaecology Faculty of Medicine, University of Bisha, Saudi Arabia

  • Ahmed Hussien Alshewered

    University of Basrah College of Medicine, Iraq

  • Sudhakar Tummala

    Department of Electronics and Communication Engineering SRM University – AP, Andhra Pradesh




  • Alphonse Laya

    Supervisor of Biochemistry Lab and PhD. students of Faculty of Science, Department of Chemistry and Department of Chemis


  • Fava Maria Giovanna


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