Inherited thrombophilia in a patient with a colorectal carcinoma-a case report.
Author(s): HrnÄÃ¡r Matej, BreznickÃ½ Jozef, Chudej Juraj, Sokol Juraj, StaÅ¡ko JÃ¡n
Background: The incidence of thrombotic complications in patients with malignancy is higher than in the general population. There is little data about the association of congenital thrombophilia with malignant disease. Methodology: We report a 48 years old patient with inherited thrombophilia (homozygous factor V Leiden and homozygous MTHFR C677T) with the manifestation of thromboembolic disease who developed colorectal carcinoma seventeen years after diagnosis of thrombotic events. Discussion: We discuss the need for cancer screening in patients with inherited thrombophilia as the need for thromboprophylaxis in patients with inherited thrombophilia and cancer. Conclusion: We now have to focus on clinical experience and think about the possibility of cancer in patients with congenital thrombophilia. In case of any suspicion, adequate investigation is needed to detect the early stage of the disease
Share this article
Submitted PhD thesis in Biotechnology at GITAM University, Vizag.
The Past Head, General Administration of Pharmaceutical Care at Ministry of Health,
Saudi Arabia Critical Care/TPN
Clinical Pharmacist Ministry of Health,
Riyadh, Saudi Arabia.
Department of Radiation Oncology
Asahi University Hospital
Gifu city, Gifu, Japan
Maher Abdel Fattah Al-Shayeb
Department of Surgical Sciences, Ajman University, UAE
Institute of Gynecology and Obstetrics, Medical University of Lodz, I Clinic of Gynecology and Gynecological Oncology (Lodz, Poland)
Citations : 61
- Euro Pub
- Google Scholar
- Medical Project Poland
- Cancer Index
- Gdansk University of Technology, Ministry Points 20