Inherited thrombophilia in a patient with a colorectal carcinoma-a case report.
Abstract
Author(s): HrnÃÂár Matej, Breznický Jozef, Chudej Juraj, Sokol Juraj, Staà ¡ko Ján
Background: The incidence of thrombotic complications in patients with malignancy is higher than in the general population. There is little data about the association of congenital thrombophilia with malignant disease. Methodology: We report a 48 years old patient with inherited thrombophilia (homozygous factor V Leiden and homozygous MTHFR C677T) with the manifestation of thromboembolic disease who developed colorectal carcinoma seventeen years after diagnosis of thrombotic events. Discussion: We discuss the need for cancer screening in patients with inherited thrombophilia as the need for thromboprophylaxis in patients with inherited thrombophilia and cancer. Conclusion: We now have to focus on clinical experience and think about the possibility of cancer in patients with congenital thrombophilia. In case of any suspicion, adequate investigation is needed to detect the early stage of the disease
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Editors List
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Prof. Elhadi Miskeen
Obstetrics and Gynaecology Faculty of Medicine, University of Bisha, Saudi Arabia
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Ahmed Hussien Alshewered
University of Basrah College of Medicine, Iraq
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Sudhakar Tummala
Department of Electronics and Communication Engineering SRM University – AP, Andhra Pradesh
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Alphonse Laya
Supervisor of Biochemistry Lab and PhD. students of Faculty of Science, Department of Chemistry and Department of Chemis
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Fava Maria Giovanna
Onkologia i Radioterapia peer review process verified at publons
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