Hallmarks of cancer stem cells in men associated cancers: a review


Author(s): Sreedhar Surampudi, Satyanarayana Swamy, Satyanarayana Rentala, Sivarama Prasad Darsi

Failure of conventional therapies is the root cause for the progression of the cancer. Intrinsic revelation states that Cancer metastasis is due to subclonal diversification of normal cells into subsets of stem like cells. These cells can be termed as stem cells of the cancer or cells that initiate cancer. These diversified cells can differentially activate and escape from the resistant mechanisms causes tumor heterogeneity. Because of these metastatic fuelling which is malignant, expresses its persistence towards treatment and provokes drug-resistant recurrence. Annihilation of these subsets of stem like cells in cancer tissues has now become a prime objective to develop and design novel classes of anti-cancer therapeutics to improve clinical efficacy. In this review, the properties and hallmark of different cancer stem cells that are responsible for disease recurrence and metastases which are elusive targets for present oncotherapies was presented.

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Awards Nomination

Editors List

  • Prof. Elhadi Miskeen

    Obstetrics and Gynaecology Faculty of Medicine, University of Bisha, Saudi Arabia

  • Ahmed Hussien Alshewered

    University of Basrah College of Medicine, Iraq

  • Sudhakar Tummala

    Department of Electronics and Communication Engineering SRM University – AP, Andhra Pradesh




  • Alphonse Laya

    Supervisor of Biochemistry Lab and PhD. students of Faculty of Science, Department of Chemistry and Department of Chemis


  • Fava Maria Giovanna


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Onkologia i Radioterapia received 208 citations as per Google Scholar report

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