Evaluating laparoscopic ovarian drilling effects on anti-mullerian hormone levels in polycystic ovarian syndrome: implications for oncological considerations in radiotherapy
Abstract
Author(s): Enas Jaleel ALobaidy*, Myasar Jasim Mohammed and Shaymaa Kanaan Mansoor
Laparoscopic Ovarian Drilling (LOD) diminishes ovarian androgen-producing tissue and decreases minor transformation to estrogens. This study aims to measure the level of Anti-Mullerian Hormone (AMH) before and after laparoscopic surgery among Women with polycystic ovarian syndrome PCOS. Thirty-five PCOS patients underwent LOD after a history of none response to medication and failed to conceive. The serum values of the AMH, testosterone, Luteinizing Hormone (LH), and the number of follicles has been assessed before and after surgery. The average total of AMH serum values was 7.2 ng/ml ± 3.5 ng/ml before the operation and 6.1 ng/ ml ± 3.2 ng/ml, 7.7 ng/ml ± 4.5 ng/ml, and 6.4 ng/ml ± 3.3 ng/ml one week, three weeks, and four months subsequently later. The mean serum values of LH were 12.6 IU ± 5.7 IU (p=0.87) before the operation and 12.7 ± 11.1 IU four months later. The mean testosterone hormone levels were 0.9 ng/ml ± 0.7 ng/ml, before and 0.7 ng/ml ± 0.8 ng/ml (p=0.86) after surgery. The reproductive rate was 26.7% per year. Laparoscopic ovarian drilling couldn't alliterate serum AMH, testosterone, and LH in infertile PCOS women, therefore has no opposing effect on the ovarian reserve.
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Editors List
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Prof. Elhadi Miskeen
Obstetrics and Gynaecology Faculty of Medicine, University of Bisha, Saudi Arabia
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Ahmed Hussien Alshewered
University of Basrah College of Medicine, Iraq
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Sudhakar Tummala
Department of Electronics and Communication Engineering SRM University – AP, Andhra Pradesh
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Alphonse Laya
Supervisor of Biochemistry Lab and PhD. students of Faculty of Science, Department of Chemistry and Department of Chemis
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Fava Maria Giovanna
Onkologia i Radioterapia peer review process verified at publons
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