Effect of target breast volume on the scattered dose to the contralateral breast during the radiotherapy of breast cancer patients

Abstract

Author(s): Nabaa A. Rasheed Naji, Alaa H. Alkazaz

This study's goal was to assess how the volume of the target breast affected how much dispersed radiation was delivered to the contralateral breat following treatment for primary breast cancer. Fifteen females have been involved in this study, they were diagnosed as having unilateral breast cancer and underwent unilateral breast lumpectomy or mastectomy. The patient’s age range (40-60) years and their mean target breast volume was (1318.5 ± 553.9) cc. breasts imaged with CT scan to produce an image that imported to the radiotherapy planning system. The three-dimensional conformal radiotherapy planning technique (3DCRT) was used for generating of therapeutic plan, where he contoured regions included the target breast, and the contralateral breast. The dose delivered was 50 or 40.05 Gy which were fractionated according to the treatment protocol of each case. The target beast volume measurement was obtained by the CT image and the mean, maximum and minimum doses of the contralateral breast were determined by the generated treatment plan. The scattered dose measurements that included the mean, maximum and minimum doses of radiation therapy to the contralateral breast pointed to a nonsignificant correlation between these measurements and the volume of the target breast (P= 0.56, 0.33, 0.47 respectively). As the breast volume increase, there is a linear negative non-significant decrease in the amount of the mean dose, maximum dose and the minimum dose that reaching the contralateral breast.

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