Dyskusja nad zastosowaniem przeciwnaczyniowej terapii podtrzymujacej u chorych na rozsianego raka jelita grubego – opis przypadku

Abstract

Author(s): Krzysztof Adamowicz, Marzena Welnicka-Jaskiewicz

Colorectal cancer is the second most common cause of cancer deaths worldwide. Although progress in the development of new drugs over the last two decades have expanded treatment options for this disease, many significant problems relating to their optimization remains to be solved. Recent advances in molecular characteristics of colorectal cancer are building the foundations for further improvement of existing drugs and the development of new targeted therapies. Bevacizumab is a recombinant humanized monoclonal antibody that selectively binds to human vascular endothelial growth factor. The results of many studies and meta-analysis showing the efficacy of bevacizumab in the first and second line treatment are inconclusive because of the variety of subgroups of patients in studies. Furthermore, still do not have any marker response to treatment with inhibitors of the anti-VEGF agents. The results of studies using bevacizumab maintenance therapy is promising, but still ambiguous.

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Editors List

  • S.SREEDHAR

    Submitted PhD thesis in Biotechnology at GITAM University, Vizag.

  • Yousef Alomi

    Yousef Alomi
    The Past Head, General Administration of Pharmaceutical Care at Ministry of Health,
    Saudi Arabia Critical Care/TPN
    Clinical Pharmacist Ministry of Health,
    Riyadh, Saudi Arabia.

  • Osamu Tanaka

    Osamu Tanaka
    Assistant Professor,
    Department of Radiation Oncology
    Asahi University Hospital
    Gifu city, Gifu, Japan

  • Maher Abdel Fattah Al-Shayeb

    Department of Surgical Sciences, Ajman University, UAE

  • Andrzej Zdziennicki

    Institute of Gynecology and Obstetrics, Medical University of Lodz, I Clinic of Gynecology and Gynecological Oncology (Lodz, Poland)

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