Czynniki prognostyczne u chorych z przerzutami do mozgu niedrobnokomorkowego raka pluca

Abstract

Author(s): Ewa Jakubowicz, Anna Patla, Elzbieta Pluta, Joanna Bockenheimer-Ruszkowska, Jerzy Władysław Mituś4 (DF), Marian Reinfuss2 (AE)

Lung carcinoma is the most common cause of brain metastases (40–60%). Patients with non-small cell lung carcinoma present with brain involvement at the time of the diagnosis in several to a dozen per cent of cases. In the course of the disease, however, brain metastases are found in 16–50% of patients. Based on literature data, the authors present prognostic factors in patients with brain metastases in non-small cell lung carcinoma. The most important factors include: performance status, presence of extracranial metastases, primary disease control, number of metastatic foci in the brain, patient’s age and sex as well as interval between the primary diagnosis and the occurrence of brain metastases. It has been demonstrated that the lung-specific Graded Prognostic Assessment (LSGPA) is probably the best prognostic index.

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