Comparison of volumetric arc (VMAT) and intensity-modulated radiation treatment for pelvic lymph nodes and bladder cancer

Abstract

Author(s): Manar M. Al Rubaie*, Mustafa S. Al Musawi and Dr Ammar Rasoul Mohammad

Background: Bladder cancer is an intricate disease associated with high morbidity and death- rates if not treated optimally. The three main components of treating bladder cancer are surgery, chemotherapy, and radiation therapy. When used for local recurrence control, external beam radiation is highly effective. The purpose of this study is to compare the benefits of using the Volumetric Arc Therapy (VMAT) technique to those of using the Intensity Modulated Radiotherapy (IMRT) technique for treating patients with bladder cancer, specifically with regard to achieving a homogeneous dose distribution for the tumor while also minimising the dose to the organs at risk. Material and Method: Patients with bladder cancer and positive lymph node were eligible for the study. This planning using IMRT and VMAT will be design to deliver 60GY to the PTV bladder cancer and 50GY to the PTV positive lymph node. The dose volume histograms were apply to quantitative evaluation of the treatment plans, including PTV, rectum, intestine, head of femur . Results: This planning for the IMRT and VMAT for PTV50 where 95% p-value (0.109) and 107% the VMAT p-value (0.006). When dose PTV60 were 95% and 107% the p-value (0.678, 0.768). The organ at risks (OARs) plan dose (intestine, rectum, RT. Head Femoral, LT. Head Femoral) that techniques IMRT and VMAT p-value (0.016, 0.146, 0.387, and 0.609). Conclusions: Our research indicates that VMAT is the most appropriate method for this time period when compared to IMRT.

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Awards Nomination

Editors List

  • Prof. Elhadi Miskeen

    Obstetrics and Gynaecology Faculty of Medicine, University of Bisha, Saudi Arabia

  • Ahmed Hussien Alshewered

    University of Basrah College of Medicine, Iraq

  • Sudhakar Tummala

    Department of Electronics and Communication Engineering SRM University – AP, Andhra Pradesh

     

     

     

  • Alphonse Laya

    Supervisor of Biochemistry Lab and PhD. students of Faculty of Science, Department of Chemistry and Department of Chemis

     

  • Fava Maria Giovanna

     

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