Comparison of LigaSure and conventional suture techniques in total abdominal hysterectomy: Impacts on postoperative pain and duration of surgery


Author(s): Atefeh Moridi, Arezoo Mehraban, Zahra Naeiji, Zahra Fahmfam

Introduction: Pain management after hysterectomy is a critical concern, and limited studies have investigated the effect of LigaSure on postoperative pain. This study aimed to compare pain levels after Total Abdominal Hysterectomy (TAH) using traditional methods versus the LigaSure device.

Methods: This registered clinical trial included 29 cancer patients undergoing TAH at an institutional tertiary hospital in Tehran, Iran, from 2021 to 2023. 16 patients underwent TAH with traditional methods, and 13 with LigaSure. Data on pain intensity (6 hours and 24 hours post-surgery), analgesic consumption, intraoperative blood loss, hospitalization length, hemoglobin drop, and cancer surgery duration were collected through patient interviews and medical records. SPSS 26 and the Mann-Whitney U test were used for analysis (Registry ID: IRCT20221109056457N1).

Results: Pain intensity at 6 hours and 24 hours post-surgery was significantly lower in the LigaSure group compared to the traditional method group (p<0.05). Surgery duration was also significantly shorter with LigaSure (p<0.05). No significant differences were found between the two groups in terms of analgesic consumption, intraoperative blood loss, hospitalization length, or hemoglobin drop (p>0.05).

Conclusion: TAH with LigaSure significantly reduces postoperative pain and cancer surgery duration compared to traditional methods. This method is recommended for women undergoing hysterectomy. However, cancer multicenter clinical trials with larger sample sizes are needed to further evaluate its benefits and potential complications.

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Awards Nomination

Editors List

  • Prof. Elhadi Miskeen

    Obstetrics and Gynaecology Faculty of Medicine, University of Bisha, Saudi Arabia

  • Ahmed Hussien Alshewered

    University of Basrah College of Medicine, Iraq

  • Sudhakar Tummala

    Department of Electronics and Communication Engineering SRM University – AP, Andhra Pradesh




  • Alphonse Laya

    Supervisor of Biochemistry Lab and PhD. students of Faculty of Science, Department of Chemistry and Department of Chemis


  • Fava Maria Giovanna


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