Co wiemy o bialkach szoku termicznego?
Author(s): BOGDAN SZYMALA, ANITA OLEJEK, PIOTR BODZEK, ALEKSANDRA DAMASIEWICZ-BODZEK, MALGORZATA KRUSZELNICKA
Heat shock proteins (Hsp) are a group of proteins, whose production is induced as a intracellular response to different kinds of stress. They maintain also homeostasis inside the cell. They are present in all cells of all species of eucaryota and procaryota. Heat shock proteins can act like antigens in many infectious diseases. Heat shock proteins also play an important role in hiperthermic therapy. They can influence either the development of atheromatous plaque in the vascular wall or neurodegenerative processes like Parkinson or Alzheimer diseases. The paper presents the characteristics of heat shock proteins, their role in the state of health and disease and possibilities of their usage in monitorig and treatment of many illnesses such as cancer.
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Institute of Gynecology and Obstetrics, Medical University of Lodz, I Clinic of Gynecology and Gynecological Oncology (Lodz, Poland)
Head of the Oncology Gynecology Clinic, Oncology Center - Instytut im. Maria Sklodowska Curie, Department in Krakow (Krakow, Poland)
Klinika Nowotworow Gornego Odcinka Uklad Digestii, Oncology Center - Institute (Warsaw, Poland)
Department of Radiotherapy, Oncology Center-Institute (Warsaw, Poland)
Head of the Obstetrics and Gynecology Clinic of the University of Otto von Guericke (Magdeburg, Germany)