Carcinomatous pachymeningitis secondary to leg ewing sarcoma: an unusual metastatic site


Author(s): Abboud Fatima Zahra, Chebihi Hassani Ghita, Ait Erraisse Mohamed, Youssoufi Moulay Ali, Bouhafa Touria, Hassouni Khalid

Introduction: We report here a case of carcinomatous pachymeningitis in a patient followed for EWING'S SARCOMA (ES) of the leg. Methods: A 17-year-old patient followed for leg Ewing's sarcoma undergoing neoadjuvant chemotherapy who presents for the management of acute and atrocious headaches of rapidly progressive onset. He had a brain MRI that showed carcinomatous pachymeningitis, the diagnosis is confirmed by a lumbar puncture of the CEREBROSPINAL FLUID (CSF) that showed the presence of cancer cells related to Ewing's sarcoma. Results: The patient was proposed for chemotherapy and craniospinal irradiation (CSI), but he died before starting his treatment. Conclusions: Carcinomatous pachymeningitis in Ewing's sarcoma is an unusual metastatic localization and its prognosis is pejorative.

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Editors List


    Submitted PhD thesis in Biotechnology at GITAM University, Vizag.

  • Yousef Alomi

    Yousef Alomi
    The Past Head, General Administration of Pharmaceutical Care at Ministry of Health,
    Saudi Arabia Critical Care/TPN
    Clinical Pharmacist Ministry of Health,
    Riyadh, Saudi Arabia.

  • Osamu Tanaka

    Osamu Tanaka
    Assistant Professor,
    Department of Radiation Oncology
    Asahi University Hospital
    Gifu city, Gifu, Japan

  • Maher Abdel Fattah Al-Shayeb

    Department of Surgical Sciences, Ajman University, UAE

  • Andrzej Zdziennicki

    Institute of Gynecology and Obstetrics, Medical University of Lodz, I Clinic of Gynecology and Gynecological Oncology (Lodz, Poland)

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