Bacterial colonization of skin profile and their relation with non-melanoma skin cancers

Abstract

Author(s): Zainab S Alzubaidy*, Mouruj A Alaubydi, Ali F Alsaadi

The skin is the largest physical barrier between attacking pathogens and the body. This study aimed to find the relationship between some popular characteristics or behaviors, and bacterial prevalence in causing different types of skin cancer. Therefore, specimens of 64 cases of different cutaneous tumors including bacterial swabs (tumor and healthy sites) are collected from each patient. The results showed that the randomly collected 64 specimens included 45 (70.3%) males and 19 (29.7%) females with no wide differences between males and females in the mean of age for both sexes. As well as, the results revealed that the difference was substantial among skin tumors which are restricted to 5 types including Squamous Cell Carcinoma (SCC), Basal Cell Carcinoma (BCC), Mycoses Fungoides (MF), Kaposis sarcoma, and Dermato fibroma in percentages 46.9%, 25.0%, 20.3%, 6.3%, and 1.6% respectively, and BCC (73.3%), SCC (75%), and KS (53.8%) are higher significantly in males than females 26.7%, 25%, 0.0% respectively. Simultaneously, the results elucidated that various non-melanoma skin cancer kinds are more prevalent in married patients 93.74%, than in unmarried 6.25%. Moreover, the findings demonstrated that there are no substantial differences among tumor patients who had chronic diseases and those who do not, in both males and females in general, but females with chronic diseases recorded a significant increase in the case of BCC only. On the other hand, the bacteriological status of both the tumor and healthy areas of each patient was investigated and the results showed no significant difference between positive and negative bacterial growth in tumor sites, while the negative growth recorded significantly increasing results in the case of healthy areas. Significant differences were found between tumor and healthy areas in the same context. Furthermore, gram-positive bacteria such as different species of the Staphylococcus genus are more dominant than gram-negative bacterial isolates which are restricted into two genera including Acinetobacter lwoffii, and Pseudomonas aeruginosa only.

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