Analysis of central vaginal cuff HDR brachytherapy using various cylinder sizes-literature review


Author(s): Giridharan Sampath*, Satheeshkumar Anbazhagan and Chandrakant D. Lokhande

Background: The technique of brachytherapy in the radiation treatment is superior modality of achieving the radiotherapy goals like maximum dose to the target area and very minimal dose to the other normal organs. But some of the difficulties in the brachytherapy procedures many of radiation therapy centers are forgot their patient’s excellent outcomes of brachytherapy techniques and some of the centers are restricted to minimal application like intracavitory, surface mould. On another side, reducing interest in brachytherapy treatment was financial issues of the institution like source cost and maintenance. Due to that there is no major research happening in that field of brachytherapy. So since 1995 brachytherapy dose calculation algorithm of TG-43 was using worldwide which is not accounting the applicator attenuation and patient heterogeneity in the treatment. The many authors are studying the applicator attenuation and applicator effect of different application using brachytherapy treatment will lead to better treatment outcomes of the patients. Aim: The main aim of this study is to review the articles around analysing the different CVS applicators and different method of dose prescriptions to get better outcome in the brachytherapy treatment. Materials: There are four scientific articles reviewed, which was analysed the various diameter of central vaginal application and various treatment length and different methods of dose prescription. Conclusion: To achieve the reduction of normal organ doses and reduction of hot spot near the vaginal surfaces, it’s better to prescribe the doses on vaginal surfaces or cylindrical surface when especially using smaller diameter cylinders.

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Editors List


    Submitted PhD thesis in Biotechnology at GITAM University, Vizag.

  • Yousef Alomi

    Yousef Alomi
    The Past Head, General Administration of Pharmaceutical Care at Ministry of Health,
    Saudi Arabia Critical Care/TPN
    Clinical Pharmacist Ministry of Health,
    Riyadh, Saudi Arabia.

  • Osamu Tanaka

    Osamu Tanaka
    Assistant Professor,
    Department of Radiation Oncology
    Asahi University Hospital
    Gifu city, Gifu, Japan

  • Maher Abdel Fattah Al-Shayeb

    Department of Surgical Sciences, Ajman University, UAE

  • Andrzej Zdziennicki

    Institute of Gynecology and Obstetrics, Medical University of Lodz, I Clinic of Gynecology and Gynecological Oncology (Lodz, Poland)

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