A review of advances in the diagnosis and treatment of metastatic atypical and anaplastic meningiomas


Author(s): Olger Nano, Supriya Peshin, Shivani Modi, Daniel Rosas

Meningiomas are primary intracranial tumors of the Central Nervous System (CNS) originating in the brain or spinal cord and have an overall incidence of about 2.3-8.3 in 100,000. Meningiomas are benign tumors mostly but atypical and anaplastic meningiomas can behave aggressively with higher chance of recurrence. Meningiomas originate from specialized meningothelial cells called arachnoid cap cells and correspond to up to 26% of all intracranial lesions. However, higher-grade meningiomas are very rare. In this article, we focus on the important literature regarding classification and molecular biology of these high grade meningiomas. In addition, we elaborate on recent advancements of diagnostic tools and novel therapeutics in the management atypical and anaplastic meningiomas.

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Awards Nomination

Editors List

  • Prof. Elhadi Miskeen

    Obstetrics and Gynaecology Faculty of Medicine, University of Bisha, Saudi Arabia

  • Ahmed Hussien Alshewered

    University of Basrah College of Medicine, Iraq

  • Sudhakar Tummala

    Department of Electronics and Communication Engineering SRM University – AP, Andhra Pradesh




  • Alphonse Laya

    Supervisor of Biochemistry Lab and PhD. students of Faculty of Science, Department of Chemistry and Department of Chemis


  • Fava Maria Giovanna


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