Familial adenomatous polyposis: Diagnosis and treatment strategies

Abstract

Author(s): Abhinov Thamminaina, Kuldeep Singh Dodamani, Abhinav Mishra, K G Patel, Sulabh Mahajan, Rupa Mazumder

Objective: The evolution of many (>100) the colorectum is covered with colorectal adenomas is a hallmark of familial adenomatous polyposis. Both clinical and molecular methods may be used to identify this condition, which can be brought on using a lineage alteration within the adenomatous polyposis coli gene.

Materials and Methods: After receiving a description of the illness, individuals should have preventive proctocolectomy at the right time with a neo reservoir, often an ileoanal pouch. People with a family history of this condition who have not yet received a diagnosis should be encouraged to attend genetic counseling sessions and sign up for the proper clinical and genetic surveillance programs.

Conclusion: The gastrointestinal system may now be studied in more depth and with greater scope because to recent advancements the use of endoscopic technologies, such as triple-balloon endoscopy, double-balloon an endoscopy and high-resolution endoscopy. Further investigation into these novel endoscopic technologies may alter the surveillance strategies for hereditary polyposis of the adenomas, notwithstanding the paucity of data.

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