Anticancer Activity of Synthesized Green Silver Nanoparticles against Human Colon Cancer Cell Lines

Abstract

Author(s): Nadhem Gharb Taher, Entisar E. AL- Abodi

This study was conducted to discuss the anticancer efficacy of synthesized AgNPs on human cancer cell (HT29) using curcumin leaf extract. A nano silver prepared by green synthesize were described by appearing a peak at 434nm using UV-visible spectroscopy. The surface morphology of prepared nanoparticles was analyzed using TEM. TEM images showed that Cur-AgNPs were measured in size of 30nm–40 nm. The MTT assay revealed that different doses of Cur-AgNPs were effectively cytotoxic against 29-HT cell lines in a time-dependent manner. Dose-dependent apoptosis and necrosis showed a similar pattern to the MTT assay. Based on the data obtained in, Cur-AgNPs have therapeutic value and a promising plan for colon cancer treatment.

Share this article

Awards Nomination

Editors List

  • Prof. Elhadi Miskeen

    Obstetrics and Gynaecology Faculty of Medicine, University of Bisha, Saudi Arabia

  • Ahmed Hussien Alshewered

    University of Basrah College of Medicine, Iraq

  • Sudhakar Tummala

    Department of Electronics and Communication Engineering SRM University – AP, Andhra Pradesh

     

     

     

  • Alphonse Laya

    Supervisor of Biochemistry Lab and PhD. students of Faculty of Science, Department of Chemistry and Department of Chemis

     

  • Fava Maria Giovanna

     

Onkologia i Radioterapia peer review process verified at publons
Indexed In
  • Directory of Open Access Journals
  • Scimago
  • SCOPUS
  • EBSCO A-Z
  • MIAR
  • Euro Pub
  • Google Scholar
  • Medical Project Poland
  • PUBMED
  • Cancer Index
  • Gdansk University of Technology, Ministry Points 20