Anticancer Activity of Synthesized Green Silver Nanoparticles against Human Colon Cancer Cell Lines
Abstract
Author(s): Nadhem Gharb Taher, Entisar E. AL- Abodi
This study was conducted to discuss the anticancer efficacy of synthesized AgNPs on human cancer cell (HT29) using curcumin leaf extract. A nano silver prepared by green synthesize were described by appearing a peak at 434nm using UV-visible spectroscopy. The surface morphology of prepared nanoparticles was analyzed using TEM. TEM images showed that Cur-AgNPs were measured in size of 30nm–40 nm. The MTT assay revealed that different doses of Cur-AgNPs were effectively cytotoxic against 29-HT cell lines in a time-dependent manner. Dose-dependent apoptosis and necrosis showed a similar pattern to the MTT assay. Based on the data obtained in, Cur-AgNPs have therapeutic value and a promising plan for colon cancer treatment.
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Editors List
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Prof. Elhadi Miskeen
Obstetrics and Gynaecology Faculty of Medicine, University of Bisha, Saudi Arabia
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Ahmed Hussien Alshewered
University of Basrah College of Medicine, Iraq
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Sudhakar Tummala
Department of Electronics and Communication Engineering SRM University – AP, Andhra Pradesh
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Alphonse Laya
Supervisor of Biochemistry Lab and PhD. students of Faculty of Science, Department of Chemistry and Department of Chemis
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Fava Maria Giovanna
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